Lh Hormone Surge And Pregnancy

Betty asks…

How do you know when you’re ovulating?

My husband and I are trying to get pregnant and I figured that if we have sex every day for a month then we should stand a good chance? I don’t know when I’m ovulating to just try then.

Pregnancy Advisor’s answers:

That’s a good idea – having sex every other day (to preserve sperm quality and quantity rather than every day) will make sure that you hit your most fertile time for pregnancy without having to chart or bother with home Ovulation Predictor Kits (OPKs) etc. Some women choose to opt for this route when TTC and fair play to them :) However, I’m a self-confessed control freak when it comes to things like this and I’ve opted to chart my temps, track my Cervical Mucus ANNNDDDD use the OPK pee-sticks! I can say that I recommend charting the temperatures each morning with a Basal Thermometer, if you were to choose only one to follow. The rise and fall in your readings every day will show you IF you’ve ovulated as it is possible to go through a cycle sometimes where no ovulation takes place. You’d be looking at having a pattern similar to the one below to let you know you have ovulated:

http://www.fertilityfriend.com/Faqs/ovulation_chart.gif

Signing up with Fertility Friend is a great idea to keep your info organised :) If you decide to use the pee-sticks, buy them cheaply and in bulk from ebay and test from about Cycle Day 10 – 20 (depending on the length of your cycle). Mine can be irregular and testing at these times always ensures I get my positive reading:

http://www.babieseverywhere.com/serendipity/uploads/firstpositiveOPK.jpg

This is when you want to baby-dance straight away and the next day too! The OPKs pick up on the surge of Lutenising Hormone (LH) which is released to trigger the release of an egg (Ovulation). I’m a “pee-on-a-stick-addict” so these work well for me!

As for Cervical Mucus – this can be a handy verification that you’re about to ovulate. Taking 1000mg Evening Primrose Oil capsules daily from the day you start your period to the day of ovulation can help to increase the amount of fertile CM you have, which is what transports the swimmers!

Stage 1: Lasting 2 – 3 days CM is Sticky or Gummy (S)
Stage 2: Lasting 2- 4 days: CM is Creamy, Milky, Lotion Like – Beginning of your fertile period (C)
Stage 3: Lasting 1-5 days: Egg white Cervical Fluid – At this time you are very fertile. (E)
Stage 4: Dry, Moist or Sticky (Infertile)

Peak fertile cervical mucus is thin and stretchy. After ovulation, progesterone abruptly suppresses the peak mucus and the mucus pattern continues with sticky mucus for a day or two, and then returns to dryness.

Wishing you lots of luck and Baby-dust for the journey ahead! ****

Nancy asks…

When is the best time to try to get pregnant?

After your period ends or before? Or anytime?

Pregnancy Advisor’s answers:

Best time to try and get pregnant is around the time you ovulate. The best way to know when you will be ovulating is by using a Ovulation Prediction Kit (OPK) These look like a pregnancy test but instead monitor the level of the hormone LH which surges about 12-24 hours before you ovulate. As soon as you get a positive you need to have as much sex as you can in that 12-48 hours.

Sandra asks…

When is the best time of day to take an ovulation predictor test?

Pregnancy Advisor’s answers:

Ovulation predictor tests test for a surge in LH (leutenizing hormone). This hormone rises during waking hours, making the best time to take the test *at least 2 hours* after you woke up.

The first link below states: late afternoon urine is the best as it contains the highest concentration of LH.

The second link below states: The best time to use these tests is between 2 and 8 p.m. First morning pee is not recommended.

In any case, the WORST time to take the test is when you first wake up. This is a good time to take a PREGNANCY test, but not an ovulation test.

Linda asks…

What’s the difference between IUI and IVF?

Difference between:

“INTRAUTERINE INSEMINATION” & “IN VETRO FERTILIZATION”?

1) cost?
2) success rate ?
3) procedure?

I know that IUI less expensive but what am i looking at?

also, I read up on each but need a breakdown of procedure if possible.

& NEED PROS & CONS OF EACH! For example, why would I go with one procedure over the other?

Seriously considering. Please Help.

Thank you,
Pam

Pregnancy Advisor’s answers:

Here is some information for you:

IUI-
When a physician places semen into the reproductive tract of the patient, the process is called artificial insemination. The type of insemination and method of sperm processing depends on the details of each case. When sperm from the patient’s husband is used, we term the process artificial insemination with husband’s sperm (AIH). When sperm is obtained from an anonymous donor, the process is termed therapeutic donor insemination (TDI). Proper timing of artificial insemination is important to the success of the process. Once it is ovulated, an egg remains fertilizable for 12-24 hours. Once deposited in the reproductive tract of a woman, sperm retains the ability to fertilize an egg for 24-72 hours. Therefore, a well-timed insemination might occur anytime between 24 hours before and 12 hours after the egg(s) is(are) released.

Usually, a single insemination is planned for the expected day of ovulation each cycle. In special situations when the number of sperm for insemination is low or the timing is uncertain we will schedule insemination on two consecutive days. The day of insemination(s) may be determined by several means. Some woman will utilize a kit that detects the LH surge in her urine. Ovulation is most likely to occur on the day after the LH surge is first appreciated. These, patients are instructed to run an LH kit and call the office to schedule insemination for 18-30 hours after the LH surge is noted. An alternative means of scheduling insemination is to monitor the LH surge utilizing blood testing. Ultrasound evaluation of follicle growth may be incorporated into cycle monitoring.

IVF-
In vitro fertilization (IVF) involves the fertilization of eggs by sperm in a dish (outside the woman’s body). The embryos which result are transferred back into the woman’s body (ET). Although it is technically possible to perform IVF without the use of fertility drugs, only one egg would be collected and the chance for pregnancy would be low. With the use of fertility drugs many eggs (ova)are retrieved, improving the chances of success.

Injectable gonadotropins are used for most IVF procedures. In order to arrive at an ideal starting point a cycle of oral contraceptive pills is often prescribed prior to beginning gonadotropin injections. In addition, many patients are pretreated with a gonadotropin releasing hormone (GnRH) agonists, for example Lupron, drugs that turns off a patient’s own hormones.

The GnRH agonist down-regulation allows injectable gonadotropins to synchronize the development of multiple follicles. GnRH agonists also prevent a woman from triggering her ovulation prematurely (before the eggs can be collected). Alternatively,a GnRH-antagonist medication may be utilized beginning a few days before oocyte collection in order to prevent premature egg release.

In a typical IVF cycle the woman begins a package of oral contraceptive pills on or before the fifth days of her period. On the 18th day of that cycle injections of Lupron are begun. A period is expected around day 26. An ultrasound and blood tests are then performed to verify that the woman is in a good “starting position” to receive the injectable gonadotropin drugs.

The dose of gonadotropins ( taken daily or twice daily) is adjusted with hopes of obtaining 12 to 15 oocytes (eggs) for use during the IVF procedure. Progress towards ovulation is monitored every few days with ultrasound and blood tests. If she has not been treated with Lupron, the woman will begin the medication Ganerelix after ultrasound has determined that her leading follicle is 12-14mm. In size. When the patient’s follicles are ripe, ovulation is triggered with an injection of human chorionic gonadotropin (hCG).

My husband and I will be trying AIH, and if that doesn’t work we will be moving on to IVF. I wish you the best of luck!

Laura asks…

what are all the functions of follicle stimulating hormone and Luteinising hormone?

Pregnancy Advisor’s answers:

FSH (follicle stimulating hormone) regulates the development, growth, pubertal maturation, and reproductive processes of the body
In both males and females, FSH stimulates the maturation of germ cells.

In males, FSH induces sertoli cells to secrete inhibin and stimulates the formation of sertoli-sertoli tight junctions (zonula occludens).

In females, FSH initiates follicular growth, specifically affecting granulosa cells. With the concomitant rise in inhibin B, FSH levels then decline in the late follicular phase. This seems to be critical in selecting only the most advanced follicle to proceed to ovulation. At the end of the luteal phase, there is a slight rise in FSH that seems to be of importance to start the next ovulatory cycle.

In both males and females, (LH) Luteinising hormone is essential for reproduction.
In females, at the time of menstruation, FSH initiates follicular growth, specifically affecting granulosa cells. With the rise in estrogens, LH receptors are also expressed on the maturing follicle that produces an increasing amount of estradiol. Eventually at the time of the maturation of the follicle, the estrogen rise leads via the hypothalamic interface to the “positive feed-back” effect, a release of LH over a 24-48 hour period. This ‘LH surge’ triggers ovulation thereby not only releasing the egg, but also initiating the conversion of the residual follicle into a corpus luteum that, in turn, produces progesterone to prepare the endometrium for a possible implantation. LH is necessary to maintain luteal function for the first two weeks. In case of a pregnancy luteal function will be further maintained by the action of hCG (a hormone very similar to LH) from the newly established pregnancy. LH supports thecal cells in the ovary that provide androgens and hormonal precursors for estradiol production.

In the male, LH acts upon the Leydig cells of the testis and is responsible for the production of testosterone, an androgen that exerts both endocrine activity and intratesticular activity on spermatogenesis.

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